Dimethylformamide dimethyl acetal → HCID 23316511, compound

HRID 1982448Notes

Reaction equation

HRID 1982448 reaction equation
[CH:1]1[C:13]2[NH:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[C:3]([C:14]([NH2:16])=[O:15])[N:2]=1.CO[CH:19](OC)[N:20]([CH3:22])[CH3:21]>>[CH3:19][N:20]([CH:22]=[N:16][C:14]([C:3]1[N:2]=[CH:1][C:13]2[NH:12][C:11]3[C:6]([C:5]=2[CH:4]=1)=[CH:7][CH:8]=[CH:9][CH:10]=3)=[O:15])[CH3:21]

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 131294659H-beta-Carboline-3-carboxamide

Product 1

HCID 23316511HCID 23316511, compound

Conditions

Temperature
115 °C

Procedure

A mixture of 1.0 g of beta-carboline-3-carboxamide and 3 ml of dimethyl-formamide-dimethylacetal is heated for 3 h at about 115° C. in an oil bath. After cooling, the crystals are collected on a glass frit and washed with 1 ml of dimethylformamide and then with 20 ml of ether. 1.2 g of N-[(dimethylamino)methylene]-beta-carboline-3-carboxamide with a m.p. of 307°-317° C. is obtained.

Workup

  1. temperatureAfter cooling
  2. customthe crystals are collected on a glass frit
  3. washwashed with 1 ml of dimethylformamide

Sources & evidence

ORD record
ord-c5d22185377c45d58f14e08a9f2595f6
Source dataset
uspto-grants-1986_06
Patent number
US04596808

Reaction notes

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