Aniline → HCID 13388361, compound

HRID 1982473Notes

Reaction equation

HRID 1982473 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:8][C:9]1[CH2:10][C:11]2([C:19](=[O:20])[O:18]C2=O)[CH2:12][CH2:13][C:14]=1[CH3:15].[CH:21]([O:24]C(C)C)(C)C>>[C:2]1([NH:1][C:21]([CH:12]2[CH:11]([C:19]([OH:18])=[O:20])[CH2:10][C:9]([CH3:8])=[C:14]([CH3:15])[CH2:13]2)=[O:24])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 6115AnilineHCID 7914Diisopropyl EtherHCID 53957614HCID 53957614, compound

Product 1

HCID 13388361HCID 13388361, compoundYield 96%

Procedure

0.9 g (0.01 mol) of aniline was reacted with 1.8 g (0.01 mol) of 3,4-dimethyl-3-cyclohexene dicarboxylic anhydride under reflux for 4 hours in isopropyl ether. The reaction mixture was cooled, and the precipitated crystals were filtered off to provide 2.6 g (yield: 96%) of the title compound.

Workup

  1. temperatureThe reaction mixture was cooled
  2. filtrationthe precipitated crystals were filtered off

Sources & evidence

ORD record
ord-e3d9294c53334d6f8123e877881f6bd7
Source dataset
uspto-grants-1986_06
Patent number
US04596826

Reaction notes

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