Hydrazine hydrate (1:1) → (1SR,8RS)-5-(2,2-Dimethyl-propyl)-6-methyl-3,4-diaza-tricyclo[6.2.1.02,7]undeca-2,4,6-triene

HRID 1985605Notes

Reaction equation

HRID 1985605 reaction equation
[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[C:3](=O)[C:2]2=O.C(OP([CH:18]([CH3:26])[C:19](=O)[CH2:20][C:21]([CH3:24])([CH3:23])[CH3:22])(=O)OCC)C.O.[NH2:28][NH2:29]>>[CH3:22][C:21]([CH3:24])([CH3:23])[CH2:20][C:19]1[C:18]([CH3:26])=[C:3]2[C:2]([CH:1]3[CH2:7][CH:4]2[CH2:5][CH2:6]3)=[N:29][N:28]=1

Participants

4

Reactant 3

HCID 24654Hydrazine hydrate (1:1)HCID 138696Bicyclo(2.2.1)heptane-2,3-dioneHCID 86617458(1,4,4-Trimethyl-2-oxo-pentyl)-phosphonic acid diethyl ester

Product 1

HCID 69059729(1SR,8RS)-5-(2,2-Dimethyl-propyl)-6-methyl-3,4-diaza-tricyclo[6.2.1.02,7]undeca-2,4,6-triene

Procedure

light-yellow oil. MS (ESI): 297.1 (MH+). Prepared from bicyclo[2.2.1]heptane-2,3-dione, (1,4,4-trimethyl-2-oxo-pentyl)-phosphonic acid diethyl ester, hydrazine monohydrate.

Sources & evidence

ORD record
ord-176fec6a1ae14e0cb5e5b253028b237f
Source dataset
uspto-grants-2009_06
Patent number
US07547697B2

Reaction notes

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