Hydrazine hydrate (1:1) → (1SR,8RS)-5-tert-Butyl-3,4-diaza-tricyclo[6.2.1.02,7]undeca-2,4,6-triene

HRID 1985607Notes

Reaction equation

HRID 1985607 reaction equation
[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[C:3](=O)[C:2]2=O.COP([CH2:16][C:17](=O)[C:18]([CH3:21])([CH3:20])[CH3:19])(=O)OC.O.[NH2:24][NH2:25]>>[C:18]([C:17]1[CH:16]=[C:3]2[C:2]([CH:1]3[CH2:7][CH:4]2[CH2:5][CH2:6]3)=[N:25][N:24]=1)([CH3:21])([CH3:20])[CH3:19]

Participants

4

Reactant 3

HCID 24654Hydrazine hydrate (1:1)HCID 138696Bicyclo(2.2.1)heptane-2,3-dioneHCID 14302170Dimethyl (3,3-dimethyl-2-oxobutyl)phosphonate

Product 1

HCID 69058595(1SR,8RS)-5-tert-Butyl-3,4-diaza-tricyclo[6.2.1.02,7]undeca-2,4,6-triene

Procedure

off-white crystalline solid. MS (EI): 245.2 (M+). Prepared from bicyclo[2.2.1]heptane-2,3-dione, (3,3-dimethyl-2-oxo-butyl)-phosphonic acid dimethyl ester, hydrazine monohydrate.

Sources & evidence

ORD record
ord-084567cbae85410e9f4a1985da07c180
Source dataset
uspto-grants-2009_06
Patent number
US07547697B2

Reaction notes

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