反应详情

温度

60 °C

3-Methoxymethoxy-4-(morpholin-4-yl)benzaldehyde (0.35 g) was dissolved in methanol (10 mL). To the mixture was added 2 mol/L hydrochloric acid (5 mL), and the mixture was stirred at 60° C. for 18 hours. To the reaction mixture was added a saturated aqueous sodium hydrogen carbonate solution, and the resulting mixture was extracted with ethyl acetate. The organic layer was washed with brine and dried over anhydrous magnesium sulfate. The solvent was removed under reduced pressure to give the title compound (0.29 g).

1. extractionthe resulting mixture was extracted with ethyl acetate
2. washThe organic layer was washed with brine
3. dry with materialdried over anhydrous magnesium sulfate
4. customThe solvent was removed under reduced pressure