Tetrahydrofuran → Methyl 3-cyclopentyl-2-[2-methyl-4-(trifluoromethyl)imidazol-1-yl]propanoate
Reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:11][Si:12]([CH3:13])([CH3:14])[N-:15][Si:16]([CH3:17])([CH3:18])[CH3:19].[CH3:1][c:2]1[nH:3][cH:4][c:5]([C:7]([F:8])([F:9])[F:10])[n:6]1.[CH:21]1([CH2:26][CH:27]([C:28](=[O:29])[O:30][CH3:31])[O:32][S:33]([C:34]([F:35])([F:36])[F:37])(=[O:38])=[O:39])[CH2:22][CH2:23][CH2:24][CH2:25]1.[Li+:20]>>[CH3:1][c:2]1[n:3]([CH:27]([CH2:26][CH:21]2[CH2:22][CH2:23][CH2:24][CH2:25]2)[C:28](=[O:29])[O:30][CH3:31])[cH:4][c:5]([C:7]([F:8])([F:9])[F:10])[n:6]1Participants
6
Sources & evidence
- ORD record
- ord-786a3002b1c342d8be40453600f4c5d2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…