Chloroform → Tert-butyl 4-hydroxypiperidine-1-carboxylate

HRID 198658Notes

Reaction equation

HRID 198658 reaction equation
[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13]([O:14][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:15].[CH3:24][CH2:25][O:26][C:27](=[O:28])[CH3:29].[CH:20]([Cl:21])([Cl:22])[Cl:23].[OH:1][CH:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][N:5]([C:13]([O:12][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:14])[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 6212ChloroformHCID 8857Ethyl AcetateHCID 79341Piperidin-4-olHCID 10219638Carbonic acid, bis(1,1-dimethylethyl) ester

Product 1

HCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylate

Sources & evidence

ORD record
ord-2cf94768c24444968df4ac46bb15f806
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…