HCID 69066270, compound → HCID 43186111, compound

HRID 1987824Notes

Reaction equation

HRID 1987824 reaction equation
[N+:1]([C:4]1[CH:16]=[CH:15][C:7]([O:8][CH:9]2[CH2:13][CH2:12][O:11][C:10]2=[O:14])=[CH:6][CH:5]=1)([O-])=O>CCO.[OH-].[Pd+2].[OH-]>[NH2:1][C:4]1[CH:16]=[CH:15][C:7]([O:8][CH:9]2[CH2:13][CH2:12][O:11][C:10]2=[O:14])=[CH:6][CH:5]=1

Participants

4

Reactant 1

HCID 69066270HCID 69066270, compound

Product 1

HCID 43186111HCID 43186111, compoundYield 99%

Reagents, catalysts & solvents 2

HCID 9942167Palladium hydroxideCatalystHCID 702EthanolSolvent

Procedure

To a solution of 3-(4-nitrophenoxy)-dihydrofuran-2-one (47 mg, 0.21 mmol) in EtOH (3 mL) was added palladium hydroxide (<1 mg). The reaction flask was evacuated and purged with H2 and then stirred at room temperature under a H2 atmosphere for 1 hour. The catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to provide the desired product (40 mg, 99%).

Workup

  1. customThe reaction flask was evacuated
  2. custompurged with H2
  3. customThe catalyst was removed by filtration
  4. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-cf7353b6bc414de9acbd82066b310e9a
Source dataset
uspto-grants-2009_06
Patent number
US07553842B2

Reaction notes

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