反应详情

To a solution of Z-N-Me-Val-N-Me-Tyr(3-tBu)-NHOMe (1.23 g, 2.33 mmol) in MeOH (20 ml), palladium hydroxide/carbon (350 mg) was added and stirred in a hydrogen atmosphere for 1 hour. Insoluble matters were removed by filtration with Celite and the filtrate was concentrated under reduced pressure to give crude N-Me-Val-N-Me-Tyr(3-tBu)-NHOMe (0.91 g).

1. customInsoluble matters were removed by filtration with Celite
2. concentrationthe filtrate was concentrated under reduced pressure