Sodium methanethiolate → HCID 18434372, compound

HRID 1988905Notes

Reaction equation

HRID 1988905 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5](CBr)=[C:4]([N+:10]([O-:12])=[O:11])[CH:3]=1.[CH3:13][S-:14].[Na+]>O1CCCC1>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:14][CH3:13])=[C:4]([N+:10]([O-:12])=[O:11])[CH:3]=1

Participants

4

Reactant 2

HCID 4378561Sodium methanethiolateHCID 127613784-Bromo-1-(bromomethyl)-2-nitrobenzene

Product 1

HCID 18434372HCID 18434372, compoundYield 105.8%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A suspension of 4-bromo-1-(bromomethyl)-2-nitrobenzene (1.0 g) and sodium methanethiolate (0.285 g) in tetrahydrofuran (20 ml) was stirred under nitrogen for 60 h. The solvent was evaporated, chloroform (50 ml) was added and the rsidual solid was removed by filtration. The filtrate was comncentrated under vacuum to give the title compound (0.89 g).

Workup

  1. customThe solvent was evaporated
  2. additionchloroform (50 ml) was added
  3. customthe rsidual solid was removed by filtration

Sources & evidence

ORD record
ord-9f04f6de723e4ac1822b9b8dab7cc130
Source dataset
uspto-grants-2010_01
Patent number
US07642276B2

Reaction notes

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