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HRID1989103

反应详情

EQUATION

反应方程式

HRID 1989103 的结构方程式

REACTANTS

反应物

2
结构：O=P(Cl)(Cl)Cl
HCID24813

Phosphoric trichloride

Cl3OP

结构：O=c1cc(C(F)(F)F)cc(-c2ccc(C(F)(F)F)cc2)[nH]1
HCID57468622

未命名化合物

PRODUCTS

生成物

1
结构：FC(F)(F)c1ccc(-c2cc(C(F)(F)F)cc(Cl)n2)cc1
HCID57468621

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 4-trifluoromethyl-6-(4-trifluoromethylphenyl)-1H-pyridin-2-one (51.5 g, 168 mmol) and phosphoryl chloride (50 mL) according to the general procedure Ia to d preparation of chlorides. Obtained as an off-white solid (53.4 g, 98%). MS (ISN) 384.1 [(M+OAc)−], 386.0 [(M+2+OAc)−]; mp 39-40° C.