Diethyl Ether → 1-[3-(Biphenyl-4-yloxy)-2-hydroxypropyl]indole-5-carbonitrile

HRID 199218Notes

Reaction equation

HRID 199218 reaction equation
[C:14]([Li:15])([CH3:16])([CH3:17])[CH3:18].[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:34][CH2:35][O:36][CH2:37][CH3:38].[O:19]1[CH:20]([CH2:22][n:23]2[cH:24][cH:25][c:26]3[cH:27][c:28]([C:32]#[N:33])[cH:29][cH:30][c:31]23)[CH2:21]1.[c:1]1(-[c:7]2[cH:8][cH:9][c:10]([OH:13])[cH:11][cH:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[cH:8][cH:9][c:10]([O:13][CH2:21][CH:20]([OH:19])[CH2:22][n:23]3[cH:24][cH:25][c:26]4[cH:27][c:28]([C:32]#[N:33])[cH:29][cH:30][c:31]34)[cH:11][cH:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 3283Diethyl EtherHCID 71034-HydroxybiphenylHCID 8028TetrahydrofuranHCID 468686361-Oxiranylmethylindole-5-carbonitrileHCID 178418306HCID 178418306, compound

Product 1

HCID 468686371-[3-(Biphenyl-4-yloxy)-2-hydroxypropyl]indole-5-carbonitrile

Sources & evidence

ORD record
ord-3f79e9e6fc9c4f7cbb32fc34555c7220
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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