HCID 178469423, compound → 6-fluoro-1H-1,2,3-benzotriazole-7-carboxylic acid

HRID 1992219Notes

Reaction equation

HRID 1992219 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]2[N:9]=[N:8][NH:7][C:6]=2[C:10]=1[C:11]([O:13]CC)=[O:12]>Cl>[F:1][C:2]1[CH:3]=[CH:4][C:5]2[N:9]=[N:8][NH:7][C:6]=2[C:10]=1[C:11]([OH:13])=[O:12]

Participants

3

Reactant 1

HCID 178469423HCID 178469423, compound

Product 1

HCID 1785246636-fluoro-1H-1,2,3-benzotriazole-7-carboxylic acidYield 90.1%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

ethyl 6-fluoro-1H-1,2,3-benzotriazole-7-carboxylate (920 mg) was heated in 6N HCl until all of the starting material disappeared. Evaporation of the HCl afforded 718 mg of a brownish solid.

Workup

  1. customEvaporation of the HCl

Sources & evidence

ORD record
ord-ff9efc54638b4c7f8f76bd61ed0e16db
Source dataset
uspto-grants-2010_01
Patent number
US07645771B2

Reaction notes

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