Hydrochloric Acid → HCID 68714555, compound

HRID 1992749Notes

Reaction equation

HRID 1992749 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[C:10]([O:14][CH3:15])[C:11]=1[O:12][CH3:13])[C:6]([OH:8])=O.[CH3:16][N:17]([CH3:32])[CH2:18][CH2:19][CH2:20][NH:21][CH2:22][C:23]([CH3:31])=[CH:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1.F[B-](F)(F)F.N1(OC(N(C)C)=[N+](C)C)C2C=CC=CC=2N=N1.Cl>>[CH3:32][N:17]([CH3:16])[CH2:18][CH2:19][CH2:20][N:21]([CH2:22][C:23]([CH3:31])=[CH:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[C:6](=[O:8])[C:5]1[CH:9]=[C:10]([O:14][CH3:15])[C:11]([O:12][CH3:13])=[C:3]([O:2][CH3:1])[CH:4]=1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 83573,4,5-Trimethoxybenzoic AcidHCID 2733207O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 68700842HCID 68700842, compound

Product 1

HCID 68714555HCID 68714555, compoundYield 13%

Procedure

Experimental condition analogous to Example 13 were used with 3,4,5-trimethoxy benzoic acid, 0.65 g (3 mmol), and N,N-Dimethyl-N′-(2-methyl-3-phenyl-ally)-propane-1,3-diamine, 0.6 g (2.5 mmol) and O-(benzotriazole-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate 1.5 g (5 mmol) to give 130 mg of a white solid as a HCl salt. Yield: 13%.

Sources & evidence

ORD record
ord-da776fea018d40d19b046ead19ba4389
Source dataset
uspto-grants-2010_01
Patent number
US07649011B2

Reaction notes

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