1-Methylpiperazine → (4-Methyl-piperazin-1-yl)-(4-nitro-2-methoxy-phenyl)methanone

HRID 1993567Notes

Reaction equation

HRID 1993567 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[C:10]([N+:12]([O-:14])=[O:13])[CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=O.[CH3:15][N:16]1[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]1>>[CH3:15][N:16]1[CH2:21][CH2:20][N:19]([C:5]([C:4]2[CH:8]=[CH:9][C:10]([N+:12]([O-:14])=[O:13])=[CH:11][C:3]=2[O:2][CH3:1])=[O:7])[CH2:18][CH2:17]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 757764-Nitro-o-anisic acid

Product 1

HCID 68541205(4-Methyl-piperazin-1-yl)-(4-nitro-2-methoxy-phenyl)methanone

Procedure

Prepared from 2-methoxy-4-nitrobenzoic acid and 1-methyl-piperazine (TPTU, CH2Cl2/CH3CN, Et3N): MS: [M+1]+=280; Anal.: CHN.

Sources & evidence

ORD record
ord-9f4a9f2734264dd88bc2636e7ab80838
Source dataset
uspto-grants-2010_01
Patent number
US07652022B2

Reaction notes

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