Piperidine → HCID 68535888, compound

HRID 1993570Notes

Reaction equation

HRID 1993570 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:12]=1)[C:7]([OH:9])=O)([O-:3])=[O:2].[NH:17]1[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1>CCCCCC.CCOC(C)=O>[N:17]1([C:7]([C:6]2[CH:10]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:12]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=2)=[O:9])[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1

Participants

4

Reactant 2

HCID 8082PiperidineHCID 6166023-Nitro-5-(trifluoromethyl)benzoic acid

Product 1

HCID 68535888HCID 68535888, compound

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Prepared from 3-nitro-5-trifluormethyl-benzoic acid and piperidine (TPTU, CH2Cl2/CH3CN, Et3N): MS: [M+1]+=303; TLC Rf=0.27 (hexane/AcOEt 7:3).

Sources & evidence

ORD record
ord-cd22f9bd15fb425da988ebe83480cc0b
Source dataset
uspto-grants-2010_01
Patent number
US07652022B2

Reaction notes

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