HRID1993587

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6329

Methylamine

CH5N

HCID21584124

Propan-2-one--dichloromethane (1/1)

C4H8Cl2O

结构：Cc1cc(NC(=O)OCc2ccccc2)ccc1Oc1cc(Cl)ncn1

HCID86605454

未命名化合物

PRODUCTS

生成物

结构：CNc1cc(Oc2ccc(NC(=O)OCc3ccccc3)cc2C)ncn1

HCID68537615

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

The title compound is prepared from [4-(6-chloro-pyrimidin-4-yloxy)-3-methyl-phenyl]-carbamic acid benzyl ester by aminomethylation (30% CH3NH2 in EtOH, 60 min, rt): M+H=363.9; Rf (acetone/CH2Cl2=3:7): 0.26.