Potassium Chlorate → HCID 178526838, compound

HRID 1993632Notes

Reaction equation

HRID 1993632 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([OH:10])=[N:8][CH:9]=1)([O-:3])=[O:2].[Cl:11]([O-])(=O)=O.[K+]>Cl.O>[Cl:11][C:6]1[C:7]([OH:10])=[N:8][CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1

Participants

5

Reactant 2

HCID 6426889Potassium ChlorateHCID 178526703HCID 178526703, compound

Product 1

HCID 178526838HCID 178526838, compoundYield 242.1%

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 962WaterSolvent

Conditions

Temperature
50 °C

Procedure

Place 5-nitro-pyridin-2-ol (20 g, 143 mmol) in concentrated HCl (100 mL). Heat to 50° C. and then dropwise add potassium chlorate (6.13 g, 50 mmol) dissolved in water (100 mL). Stir at 50° C. for 30 min. Cool the reaction in an ice bath. Filter off the solid and wash with water. Dry thoroughly to yield 21.13 g (85%) of 3-chloro-5-nitro-pyridin-2-ol. MS(ES): m/z=173 [M+H].

Workup

  1. temperatureCool
  2. customthe reaction in an ice bath
  3. filtrationFilter off the solid
  4. washwash with water
  5. customDry thoroughly

Sources & evidence

ORD record
ord-87871a59ec154ffd9e156e56c34ac9da
Source dataset
uspto-grants-2010_01
Patent number
US07652015B2

Reaction notes

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