反应详情

温度

90 °C

Add ammonium formate (1.55 mmol, 0.1 g) and palladium (Carbon) 10% (0.031 mmol) over a solution of 2,2-dimethyl-1-[4-(4-methyl-5-nitro-pyridin-2-yl)-piperazin-1-yl]-propan-1-one (0.31 mmol, 0.09 g) in 2 mL of ethanol. Stir the solution for an hour at 90° C. Cool down and filter through a pad of Celite®, and concentrate under reduced pressure. Residue can be used without further purification. MS(ES): m/z=277 [M+H].

1. temperatureCool down
2. filtrationfilter through a pad of Celite®
3. concentrationconcentrate under reduced pressure
4. customResidue can be used without further purification