Sodium Hydroxide → HCID 68690292, compound

HRID 1994424Notes

Reaction equation

HRID 1994424 reaction equation
Br[CH2:2][CH:3]([O:7][CH2:8][CH3:9])[O:4][CH2:5][CH3:6].[CH:10]1([NH2:14])[CH2:13][CH2:12][CH2:11]1.[OH-].[Na+]>>[CH:10]1([NH:14][CH2:2][CH:3]([O:7][CH2:8][CH3:9])[O:4][CH2:5][CH3:6])[CH2:13][CH2:12][CH2:11]1

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 74852Ethane, 2-bromo-1,1-diethoxy-HCID 75645Cyclobutylamine

Product 1

HCID 68690292HCID 68690292, compound

Procedure

A solution of 1.75 ml (11.65 mmol) of 1-bromo-2,2-diethoxyethane and 2 ml (23.3 mmol) of cyclobutylamine was heated at 80° C. in a closed vessel overnight. The reaction mixture was mixed with 40% NaOH (in H2O) and extracted, with ether. The organic phase was isolated, dried (MgSO4) and concentrated in vacuo. 2.39 g of substance were obtained as an orange liquid.

Workup

  1. extractionextracted, with ether
  2. customThe organic phase was isolated
  3. dry with materialdried (MgSO4)
  4. concentrationconcentrated in vacuo
  5. custom2.39 g of substance were obtained as an orange liquid

Sources & evidence

ORD record
ord-9707ab9c9f5b4599a1d55ace1be0ae1b
Source dataset
uspto-grants-2010_01
Patent number
US07652007B2

Reaction notes

Loading…