反应详情

183 g of (1-methylcyclopropyl)-glyoxylic acid tert-butylamide and 112 g of thiocarbohydrazide are added to a mixture of 1 liter of 1 N HCl and 1 liter of ethanol. The mixture is refluxed for 8 hours; it is subsequently cooled and diluted with 2 liters of H2O and the crystals are filtered off with suction. White crystals having a yellow lustre are obtained and these are dried.

1. temperatureThe mixture is refluxed for 8 hours
2. temperatureit is subsequently cooled
3. filtrationthe crystals are filtered off with suction
4. customare obtained
5. customthese are dried