Hydrochloric Acid → HCID 135759124, compound

HRID 1995282Notes

Reaction equation

HRID 1995282 reaction equation
[NH2:1][C:2]1[CH:16]=[C:15]([N+:17]([O-:19])=[O:18])[CH:14]=[CH:13][C:3]=1[NH:4][C:5]1[C:9]([C:10]#[N:11])=[CH:8][N:7]([CH3:12])[N:6]=1.[ClH:20]>C(O)(C)C>[ClH:20].[NH2:11][C:10]1[C:9]2[C:5](=[N:6][N:7]([CH3:12])[CH:8]=2)[NH:4][C:3]2[CH:13]=[CH:14][C:15]([N+:17]([O-:19])=[O:18])=[CH:16][C:2]=2[N:1]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 12888760HCID 12888760, compound

Product 1

HCID 135759124HCID 135759124, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

3-(2-Amino-4-nitroanilino)-1-methylpyrazole-4-carbonitrile (250 mg) was heated under reflux in a mixture of isopropanol (10 ml) and concentrated hydrochloric acid (1 ml) for 20 hours. The solution was evaporated under reduced pressure and the residue crystallised from methylated spirits to give the title compound m.p. >260°.

Workup

  1. customThe solution was evaporated under reduced pressure
  2. customthe residue crystallised from methylated spirits

Sources & evidence

ORD record
ord-3b70f82f00a748819341bb0c1382906a
Source dataset
uspto-grants-1983_09
Patent number
US04404137

Reaction notes

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