Hydrochloric Acid → HCID 70524131, compound

HRID 1995779Notes

Reaction equation

HRID 1995779 reaction equation
[CH2:1]([CH:8]1[C:13](=O)[CH2:12][CH2:11][CH2:10][C:9]1=[O:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:16]1([CH3:27])[CH:21]=[CH:20][C:19]([S:22]([NH:25][NH2:26])(=[O:24])=[O:23])=[CH:18][CH:17]=1.Cl>CO>[C:16]1([CH3:27])[CH:17]=[CH:18][C:19]([S:22]([NH:25][N:26]=[C:13]2[CH2:12][CH2:11][CH2:10][C:9](=[O:15])[CH:8]2[CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)(=[O:23])=[O:24])=[CH:20][CH:21]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 15303P-ToluenesulfonylhydrazideHCID 6087402-benzylcyclohexane-1,3-dione

Product 1

HCID 70524131HCID 70524131, compoundYield 15.8%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1-benzyl cyclohexane-2,6-dione (17.25 g), p-toluenesulfonylhydrazine (16.52 g) in methanol (290 ml) was treated with concentrated HCl (1 ml) and left at room temperature for 48 hours. Evaporation of the solvent under reduced pressure and crystallization of the residue gave 1-benzylcyclohexane-2,6-dione mono-p-toluenesulfonylhydrazone (5 g) m.p. 172°-3° C.

Workup

  1. customEvaporation of the solvent
  2. customunder reduced pressure and crystallization of the residue

Sources & evidence

ORD record
ord-a0372b8d9c1e4eb79dadf0350633e1d7
Source dataset
uspto-grants-1983_09
Patent number
US04405810

Reaction notes

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