Hydrochloric Acid → Hydrochloric Acid

HRID 199612Notes

Reaction equation

HRID 199612 reaction equation
[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:54][OH:55].[CH:50]([Cl:51])([Cl:52])[Cl:53].[ClH:1].[ClH:2].[NH2:3][CH:4]1[CH2:5][CH2:6][N:7]([CH2:10][CH2:11][n:12]2[c:13](=[O:24])[cH:14][cH:15][c:16]3[n:17][cH:18][c:19]([O:22][CH3:23])[cH:20][c:21]23)[CH2:8][CH2:9]1.[Na+:49].[O-:45][C:46]([OH:47])=[O:48].[O:32]=[C:33]1[NH:34][c:35]2[c:36]([cH:39][cH:40][c:41]([CH:43]=[O:44])[n:42]2)[O:37][CH2:38]1>>[ClH:1].[NH:3]([CH:4]1[CH2:5][CH2:6][N:7]([CH2:10][CH2:11][n:12]2[c:13](=[O:24])[cH:14][cH:15][c:16]3[n:17][cH:18][c:19]([O:22][CH3:23])[cH:20][c:21]23)[CH2:8][CH2:9]1)[CH2:43][c:41]1[cH:40][cH:39][c:36]2[c:35]([n:42]1)[NH:34][C:33](=[O:32])[CH2:38][O:37]2

Participants

10

Reactant 8

HCID 313Hydrochloric Acid2×HCID 769Bicarbonate IonHCID 887MethanolHCID 923Sodium ionHCID 6212ChloroformHCID 8471TriethylamineHCID 218737373-Oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-6-carbaldehydeHCID 578151881-(2-(4-aminopiperidin-1-yl)ethyl)-7-methoxy-1,5-naphthyridin-2(1H)-one

Product 2

HCID 313Hydrochloric AcidHCID 250320771-(2-(4-((3-oxo-3,4-dihydro-2H-pyrido(3,2-b)(1,4)oxazin-6-yl)methylamino)piperidin-1-yl)ethyl)-7-methoxy-1,5-naphthyridin-2(1H)-one

Sources & evidence

ORD record
ord-d1f4b266f219406082acb324529e64e6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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