tert-butyl (R)-3-amino-3-methylpyrrolidine-1-carboxylate → HCID 118436056, compound

HRID 1996588Notes

Reaction equation

HRID 1996588 reaction equation
[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:14][C@@:11]([NH2:13])([CH3:12])[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3].[NH2:15][c:16]1[n:21][cH:20][c:19]([c:22]2[c:27]([CH2:28][CH2:29]I)[c:26](Cl)[n:25][c:24]([N:30]3[CH2:35][CH2:34][O:33][CH2:32][CH2:31]3)[n:23]2)[cH:18][n:17]1>>[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:14][C@:11]([N:13]2[c:26]3[c:27]([c:22]([c:19]4[cH:20][n:21][c:16]([NH2:15])[n:17][cH:18]4)[n:23][c:24]([N:30]5[CH2:35][CH2:34][O:33][CH2:32][CH2:31]5)[n:25]3)[CH2:28][CH2:29]2)([CH3:12])[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3]

Participants

6

Reactant 2

HCID 86328912tert-butyl (R)-3-amino-3-methylpyrrolidine-1-carboxylateHCID 178508375HCID 178508375, compound

Product 1

HCID 118436056HCID 118436056, compound

Reagents, catalysts & solvents 3

HCID 81531DiisopropylethylamineReagentHCID 679Dimethyl SulfoxideSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
90 °C

Sources & evidence

ORD record
ord-d74bf4c46bd54ffab9e2874a0a77e3af
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

Loading…