Pyridine → N-cyclobutyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide
Reaction equation
[CH3:6][c:7]1[c:8](-[n:16]2[cH:17][n:18][c:19]3[cH:20][cH:21][c:22]([N:27]4[CH2:28][CH2:29][N:30]([CH3:33])[CH2:31][CH2:32]4)[cH:23][c:24]3[c:25]2=[O:26])[cH:9][c:10]([C:11](=[O:12])[OH:13])[cH:14][cH:15]1.[CH:34]1([NH2:38])[CH2:35][CH2:36][CH2:37]1.[P:1]([Cl:2])([Cl:3])([Cl:4])=[O:5].[cH:39]1[cH:40][cH:41][n:42][cH:43][cH:44]1>>[CH3:6][c:7]1[c:8](-[n:16]2[cH:17][n:18][c:19]3[cH:20][cH:21][c:22]([N:27]4[CH2:28][CH2:29][N:30]([CH3:33])[CH2:31][CH2:32]4)[cH:23][c:24]3[c:25]2=[O:26])[cH:9][c:10]([C:11](=[O:13])[NH:38][CH:34]2[CH2:35][CH2:36][CH2:37]2)[cH:14][cH:15]1Participants
5
Sources & evidence
- ORD record
- ord-20efc8643f2c400399ec3409ad6584a2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…