4-(4,6-Dichloropyrimidin-2-yl)morpholine → HCID 178452014, compound

HRID 1998121Notes

Reaction equation

HRID 1998121 reaction equation
Clc1[n:6][c:5]([N:7]2[CH2:12][CH2:11][O:10][CH2:9][CH2:8]2)[n:4][c:2]([Cl:3])[cH:1]1.[CH3:13][C:14]([O:17][C:18]([N:20]1[CH2:28][C:23]2([NH:27][C:26](=O)[O:25][CH2:24]2)[CH2:22][CH2:21]1)=[O:19])([CH3:16])[CH3:15]>>[CH3:13][C:14]([O:17][C:18]([N:20]1[CH2:28][C:23]([NH:27][c:26]2[n:6][c:5]([N:7]3[CH2:12][CH2:11][O:10][CH2:9][CH2:8]3)[n:4][c:2]([Cl:3])[cH:1]2)([CH2:24][OH:25])[CH2:22][CH2:21]1)=[O:19])([CH3:16])[CH3:15]

Participants

6

Reactant 2

HCID 27720684-(4,6-Dichloropyrimidin-2-yl)morpholineHCID 178451640HCID 178451640, compound

Product 1

HCID 178452014HCID 178452014, compound

Reagents, catalysts & solvents 3

HCID 2724141Tetrabutylammonium FluorideReagentHCID 31374DimethylacetamideSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-8598cde63c6d4271b9bfb609679e2b1c
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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