1,2-Dichloroethane → 3-Fluoro-4-(5-(1-phenylcyclopropyl)-thiazolo[5,4-b]pyridine-2-yl)benzonitrile
Reaction equation
[CH3:33][C:34]#[N:35].[CH3:43][CH2:44][N:45]([CH2:46][CH3:47])[CH2:48][CH3:49].[Cl:29][CH2:30][CH2:31][Cl:32].[Cl:36][S:37]([N:38]=[C:39]=[O:40])(=[O:41])=[O:42].[Cl:50][CH2:51][Cl:52].[F:1][c:2]1[cH:3][c:4]([C:5]([OH:6])=[O:7])[cH:8][cH:9][c:10]1-[c:11]1[s:12][c:13]2[n:14][c:15]([C:20]3([c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[CH2:21][CH2:22]3)[cH:16][cH:17][c:18]2[n:19]1>>[F:1][c:2]1[cH:3][c:4]([C:5]#[N:35])[cH:8][cH:9][c:10]1-[c:11]1[s:12][c:13]2[n:14][c:15]([C:20]3([c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[CH2:21][CH2:22]3)[cH:16][cH:17][c:18]2[n:19]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-90c37c0619374b379c570e968e513ecf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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