4-(4,6-Dichloropyrimidin-2-yl)morpholine → HCID 178452113, compound

HRID 1999705Notes

Reaction equation

HRID 1999705 reaction equation
[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:15][C:11]([CH2:13][OH:14])([NH2:12])[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3].Cl[c:16]1[n:22][c:21]([N:23]2[CH2:28][CH2:27][O:26][CH2:25][CH2:24]2)[n:20][c:18]([Cl:19])[cH:17]1>>[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:15][C:11]([CH2:13][O:14][c:16]2[n:22][c:21]([N:23]3[CH2:28][CH2:27][O:26][CH2:25][CH2:24]3)[n:20][c:18]([Cl:19])[cH:17]2)([NH2:12])[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3]

Participants

6

Reactant 2

HCID 27720684-(4,6-Dichloropyrimidin-2-yl)morpholineHCID 24730317tert-Butyl 3-amino-3-(hydroxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 178452113HCID 178452113, compound

Reagents, catalysts & solvents 3

HCID 79724-MethylmorpholineReagentHCID 679Dimethyl SulfoxideSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-01cd21d1c2e24f6da0568f4cefe52919
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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