HCID 14653160, compound → HCID 178467397, compound

HRID 2000345Notes

Reaction equation

HRID 2000345 reaction equation
[CH3:1][C@H:2]([c:4]1[c:9]([I:10])[cH:8][cH:7][cH:6][cH:5]1)[OH:3].[CH3:11][N:12]([C:43]([O:45][C:46]([CH3:49])([CH3:48])[CH3:47])=[O:44])[CH2:13][c:14]1[c:21]([c:22]2[n:42][c:41](Br)[c:25]([N:26]([C:34]([O:36][C:37]([CH3:40])([CH3:39])[CH3:38])=[O:35])[C:27]([O:29][C:30]([CH3:33])([CH3:32])[CH3:31])=[O:28])[n:24][cH:23]2)[c:18]([C:19]#[N:20])[n:16]([CH3:17])[n:15]1>>[CH3:1][CH:2]([c:4]1[c:9]([I:10])[cH:8][cH:7][c:6](F)[cH:5]1)[O:3][c:41]2[c:25]([N:26]([C:34]([O:36][C:37]([CH3:40])([CH3:39])[CH3:38])=[O:35])[C:27]([O:29][C:30]([CH3:33])([CH3:32])[CH3:31])=[O:28])[n:24][cH:23][c:22]([c:21]3[c:18]([C:19]#[N:20])[n:16]([CH3:17])[n:15][c:14]3[CH2:13][N:12]([C:43]([O:45][C:46]([CH3:49])([CH3:48])[CH3:47])=[O:44])[CH3:11])[n:42]2

Participants

6

Reactant 2

HCID 14653160HCID 14653160, compoundHCID 178483108HCID 178483108, compound

Product 1

HCID 178467397HCID 178467397, compound

Reagents, catalysts & solvents 3

HCID 4339838N'''-(1,1-Dimethylethyl)-N,N',N''-tris(tris(dimethylamino)phosphoranylidene)phosphorimidic triamideReagentHCID 8028TetrahydrofuranSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
80 °C

Sources & evidence

ORD record
ord-e6a16cd15fdf4794b2d098d14bdf68cb
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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