2-Pyridineacetic acid → 2-pyridin-2-yl-N-[5-[[(1S,3R)-3-[5-[(2-pyridin-2-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]cyclopentyl]methyl]-1,3,4-thiadiazol-2-yl]acetamide
Reaction equation
[OH:1][C:2]([CH2:4][c:5]1[n:10][cH:9][cH:8][cH:7][cH:6]1)=[O:3].[NH2:11][c:12]1[s:28][c:15]([CH2:16][C@@H:17]2[CH2:21][C@H:20]([c:22]3[s:27][c:25]([NH2:26])[n:24][n:23]3)[CH2:19][CH2:18]2)[n:14][n:13]1>>[O:3]=[C:2]([NH:11][c:12]1[s:28][c:15]([CH2:16][C@@H:17]2[CH2:21][C@H:20]([c:22]3[s:27][c:25]([NH:26]C(Cc4ncccc4)=[O:1])[n:24][n:23]3)[CH2:19][CH2:18]2)[n:14][n:13]1)[CH2:4][c:5]5[n:10][cH:9][cH:8][cH:7][cH:6]5Participants
7
Reactant 2
Product 1
Reagents, catalysts & solvents 4
Conditions
- Temperature
- 25 °C
Sources & evidence
- ORD record
- ord-a788d457464b4b67b8720f5ddc33db4e
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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