Allyl Alcohol → 1,5-Dimethyl-3-prop-2-enoxypyrazole

HRID 2004374Notes

Reaction equation

HRID 2004374 reaction equation
[OH:1][CH2:2][CH:3]=[CH2:4].[CH3:5][c:6]1[n:10]([CH3:11])[n:9][c:8](Br)[cH:7]1>>[CH3:5][c:6]1[n:10]([CH3:11])[n:9][c:8]([O:1][CH2:2][CH:3]=[CH2:4])[cH:7]1

Participants

9

Reactant 2

HCID 7858Allyl AlcoholHCID 217240463-Bromo-1,5-dimethyl-1H-pyrazole

Product 1

HCID 1311336121,5-Dimethyl-3-prop-2-enoxypyrazole

Reagents, catalysts & solvents 6

HCID 962WaterReagentHCID 62657Potassium Phosphate, TribasicReagentHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)CatalystHCID 5469571,4,7-Trimethyl-1,4,7-triazacyclononaneCatalystHCID 312751,4-DioxaneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-6f141b8c6829436fa589c81ff59443db
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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