3-Azetidinol, 1-propyl- → HCID 178456407, compound

HRID 2004907Notes

Reaction equation

HRID 2004907 reaction equation
[CH3:1][CH2:2][CH2:3][N:4]1[CH2:8][CH:6]([OH:7])[CH2:5]1.[CH3:9][O:10][c:11]1[cH:16][cH:15][c:14]([C:17]([CH:29]([c:30]2[cH:35][cH:34][c:33](I)[cH:32][cH:31]2)[O:28][c:27]([c:20]34)[cH:26][c:23]([O:24][CH3:25])[cH:22][cH:21]3)=[C:18]4[CH3:19])[cH:13][cH:12]1>>[CH3:1][CH2:2][CH2:3][N:4]1[CH2:8][CH:6]([O:7][c:33]2[cH:34][cH:35][c:30]([CH:29]3[C:17]([c:14]4[cH:15][cH:16][c:11]([O:10][CH3:9])[cH:12][cH:13]4)=[C:18]([CH3:19])[c:20]([c:27]5[O:28]3)[cH:21][cH:22][c:23]([O:24][CH3:25])[cH:26]5)[cH:31][cH:32]2)[CH2:5]1

Participants

7

Reactant 2

HCID 543491323-Azetidinol, 1-propyl-HCID 178488476HCID 178488476, compound

Product 1

HCID 178456407HCID 178456407, compound

Reagents, catalysts & solvents 4

HCID 23683543Potassium t-amylateReagentHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)CatalystHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-d79ff9f8ba324170b5cb4f47e1da7aaf
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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