Hydrochloric Acid → 5-(difluoromethyl)pyridin-3-amine
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[cH:9][n:10][cH:11][c:12]([CH:14]([F:15])[F:16])[cH:13]1)([CH3:5])([CH3:6])[CH3:17].[CH3:19][CH2:20][OH:21].[CH3:22][CH2:23][O:24][C:25](=[O:26])[CH3:27].[ClH:18]>>[NH2:7][c:8]1[cH:9][n:10][cH:11][c:12]([CH:14]([F:15])[F:16])[cH:13]1Participants
5
Sources & evidence
- ORD record
- ord-8b9a4c87288348ce8b5a5f986ab7829a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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