Dimethylformamide → 6-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-N-(3-methyl-oxetan-3-yl)-nicotinamide
Reaction equation
[C:26]([n:27]1[cH:28][cH:29][n:30][cH:31]1)([n:32]1[cH:33][cH:34][n:35][cH:36]1)=[O:37].[CH3:38][C:39]1([NH2:43])[CH2:40][O:41][CH2:42]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][o:10][c:11]([CH2:24][OH:25])[c:12]2[CH2:13][O:14][c:15]2[n:16][cH:17][c:18]([C:19](=[O:20])[OH:21])[cH:22][cH:23]2)[cH:6][cH:7]1.[O:44]=[CH:45][N:46]([CH3:47])[CH3:48]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][o:10][c:11]([CH2:24][OH:25])[c:12]2[CH2:13][O:14][c:15]2[n:16][cH:17][c:18]([C:19](=[O:21])[NH:43][C:39]3([CH3:38])[CH2:40][O:41][CH2:42]3)[cH:22][cH:23]2)[cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-2c9c57b2e1a54c67bbc7979a33b3705f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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