2-(Trifluoromethyl)acrylic acid → (2R)-3,3,3-trifluoro-2-methylpropanoic acid

HRID 2007837Notes

Reaction equation

HRID 2007837 reaction equation
[OH:1][C:2]([C:4]([C:6]([F:9])([F:8])[F:7])=[CH2:5])=[O:3]>>[CH3:5][C@@H:4]([C:6]([F:9])([F:8])[F:7])[C:2]([OH:1])=[O:3]

Participants

5

Reactant 1

HCID 5876942-(Trifluoromethyl)acrylic acid

Product 1

HCID 15971430(2R)-3,3,3-trifluoro-2-methylpropanoic acid

Reagents, catalysts & solvents 3

HCID 16211330Borate(1-), tetrafluoro-, hydrogen, compd. with 1,1'-oxybis(ethane) (1:1:1)ReagentHCID 3776IsopropanolSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-18324901b1bf4bafa0e9dbd8ebb5055a
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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