7-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-5-nitroisoquinolin-1(2H)-one → 5-amino-7-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-3,4-dihydroisoquinolin-1(2H)-one
Reaction equation
[CH3:1][c:2]1[c:7]([c:8]2[cH:18][c:17]([N+:19]([O-])=O)[c:16]([c:10]3[cH:9]2)[CH:15]=[CH:14][NH:13][C:11]3=[O:12])[n:5]([CH3:6])[n:4][n:3]1>>[CH3:1][c:2]1[c:7]([c:8]2[cH:9][c:10]([c:16]3[c:17]([NH2:19])[cH:18]2)[C:11](=[O:12])[NH:13][CH2:14][CH2:15]3)[n:5]([CH3:6])[n:4][n:3]1Participants
6
Reactant 1
Product 1
Reagents, catalysts & solvents 4
Conditions
- Temperature
- 30 °C
Sources & evidence
- ORD record
- ord-686eced2340f4886bc5d2ba45b6a152c
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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