3-Cyanophenylboronic acid → 3-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile
Reaction equation
[Cl:1][c:2]1[c:10]([c:6]2[n:5][cH:4][n:3]1)[c:9](I)[cH:8][nH:7]2.OB([c:11]1[cH:16][c:15]([C:17]#[N:18])[cH:14][cH:13][cH:12]1)O>>[Cl:1][c:2]1[c:10]([c:6]2[n:5][cH:4][n:3]1)[c:9]([c:11]3[cH:16][c:15]([C:17]#[N:18])[cH:14][cH:13][cH:12]3)[cH:8][nH:7]2Participants
7
Reactant 2
Product 1
Reagents, catalysts & solvents 4
Conditions
- Temperature
- 50 °C
Sources & evidence
- ORD record
- ord-3d7268aa8f8b4f1b9fa4162c9f19acce
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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