Tert-butyl 2-hydroxyacetate → HCID 178429104, compound

HRID 2012329Notes

Reaction equation

HRID 2012329 reaction equation
[CH3:1][c:2]1[n:7][n:5]([CH3:6])[c:4](Br)[cH:3]1.[CH3:8][C:9]([O:12][C:13]([CH2:15][OH:16])=[O:14])([CH3:11])[CH3:10]>>[CH3:1][c:2]1[n:7][n:5]([CH3:6])[c:4]([O:16][CH2:15][C:13]([O:12][C:9]([CH3:11])([CH3:10])[CH3:8])=[O:14])[cH:3]1

Participants

8

Reactant 2

HCID 11815394Tert-butyl 2-hydroxyacetateHCID 217240315-Bromo-1,3-dimethyl-1H-pyrazole

Product 1

HCID 178429104HCID 178429104, compound

Reagents, catalysts & solvents 5

HCID 10796Cesium carbonateReagentHCID 167845palladium(II) acetateCatalystHCID 11547931BippyPhosCatalystHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-3561a6c7061a47fcafd595d8c4a0a841
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

Loading…