Tert-butyl 2-hydroxyacetate → HCID 178429104, compound

HRID 2012346Notes

Reaction equation

HRID 2012346 reaction equation
[CH3:1][C:2]([O:5][C:6]([CH2:8][OH:9])=[O:7])([CH3:4])[CH3:3].[CH3:10][c:11]1[n:16][n:14]([CH3:15])[c:13](Br)[cH:12]1>>[CH3:10][c:11]1[n:16][n:14]([CH3:15])[c:13]([O:9][CH2:8][C:6]([O:5][C:2]([CH3:4])([CH3:3])[CH3:1])=[O:7])[cH:12]1

Participants

7

Reactant 2

HCID 11815394Tert-butyl 2-hydroxyacetateHCID 217240315-Bromo-1,3-dimethyl-1H-pyrazole

Product 1

HCID 178429104HCID 178429104, compound

Reagents, catalysts & solvents 4

HCID 516892Sodium BicarbonateReagentHCID 178492612HCID 178492612, compoundCatalystHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-c9a42a7d9bc747a698dccae3f633a835
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

Loading…