tert-Butyl carbamate → HCID 95913793, compound

HRID 2012431Notes

Reaction equation

HRID 2012431 reaction equation
[CH3:1][C:2]([O:5][C:6]([NH2:8])=[O:7])([CH3:4])[CH3:3].Br[c:9]1[cH:13][s:12][n:11][cH:10]1>>[CH3:1][C:2]([O:5][C:6]([NH:8][c:9]1[cH:13][s:12][n:11][cH:10]1)=[O:7])([CH3:4])[CH3:3]

Participants

8

Reactant 2

HCID 77922tert-Butyl carbamateHCID 52003584-Bromo-isothiazole

Product 1

HCID 95913793HCID 95913793, compound

Reagents, catalysts & solvents 5

HCID 33931062,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineReagentHCID 167845palladium(II) acetateCatalystHCID 11618717Di-tert-butyl(2',4',6'-tris(propan-2-yl)-(1,1'-biphenyl)-2-yl)phosphaneCatalystHCID 64052-Methyl-2-butanolSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-ba0e2e1624484fedab5a32cdc8e18e56
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

Loading…