Water → 4-[(3-Chloro-4-fluorophenyl)amino]-6-({[(diethoxyphosphoryl)methyl]carbonyl}amino)-7-cyclopropylmethoxyquinazoline
Reaction equation
[CH2:8]([CH3:9])[O:10][P:11](=[O:12])([O:13][CH2:14][CH3:15])[CH2:16][C:17](=[O:18])[OH:19].[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:46][N:47]([CH3:48])[CH:49]=[O:50].[NH2:20][c:21]1[cH:22][c:23]2[c:24]([NH:36][c:37]3[cH:38][c:39]([Cl:44])[c:40]([F:43])[cH:41][cH:42]3)[n:25][cH:26][n:27][c:28]2[cH:29][c:30]1[O:31][CH2:32][CH:33]1[CH2:34][CH2:35]1.[OH2:45]>>[CH2:8]([CH3:9])[O:10][P:11](=[O:12])([O:13][CH2:14][CH3:15])[CH2:16][C:17](=[O:19])[NH:20][c:21]1[cH:22][c:23]2[c:24]([NH:36][c:37]3[cH:38][c:39]([Cl:44])[c:40]([F:43])[cH:41][cH:42]3)[n:25][cH:26][n:27][c:28]2[cH:29][c:30]1[O:31][CH2:32][CH:33]1[CH2:34][CH2:35]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6d3f8e13e2924e188e62dd23ca85e7b9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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