Tetrahydrofuran → 4-[2-(4-Methylpiperazin-1-yl)ethyl]aniline

HRID 201318Notes

Reaction equation

HRID 201318 reaction equation
[Al+3:19].[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[CH2:10][c:11]2[cH:12][cH:13][c:14]([NH2:15])[cH:16][cH:17]2)[CH2:6][CH2:7]1.[H-:18].[H-:21].[H-:22].[H-:23].[Li+:20]>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([CH2:8][CH2:10][c:11]2[cH:12][cH:13][c:14]([NH2:15])[cH:16][cH:17]2)[CH2:6][CH2:7]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 167730792-(4-Aminophenyl)-1-(4-methylpiperazin-1-yl)ethan-1-one

Product 1

HCID 242554804-[2-(4-Methylpiperazin-1-yl)ethyl]aniline

Sources & evidence

ORD record
ord-db8f2420d93d4ffa9687ab6a6cbd5262
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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