HRID201619

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID8471

Triethylamine

C6H15N

HCID89602

Bromoacetyl chloride

C2H2BrClO

结构：CN(Cc1ccc(C(F)(F)F)c(F)c1)C1CNCC1c1ccc(Cl)c(Cl)c1

HCID75231672

未命名化合物

PRODUCTS

生成物

结构：CN(Cc1ccc(C(F)(F)F)c(F)c1)C1CN(C(=O)CBr)CC1c1ccc(Cl)c(Cl)c1

HCID72253469

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-15d629fb8df34c80bd7ddbefb472b5ab
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (6/10)

反应 SMILES

[Br:1][CH2:2][C:3](=[O:4])[Cl:5].[CH2:33]([N:34]([CH2:35][CH3:36])[CH2:37][CH3:38])[CH3:39].[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[Cl:6][c:7]1[cH:8][c:9]([CH:14]2[CH:15]([N:19]([CH3:20])[CH2:21][c:22]3[cH:23][c:24]([F:32])[c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]3)[CH2:16][NH:17][CH2:18]2)[cH:10][cH:11][c:12]1[Cl:13]>>[Br:1][CH2:2][C:3](=[O:4])[N:17]1[CH2:16][CH:15]([N:19]([CH3:20])[CH2:21][c:22]2[cH:23][c:24]([F:32])[c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]2)[CH:14]([c:9]2[cH:8][c:7]([Cl:6])[c:12]([Cl:13])[cH:11][cH:10]2)[CH2:18]1