HCID 178483110, compound → HCID 178486944, compound

HRID 2016458Notes

Reaction equation

HRID 2016458 reaction equation
[CH3:1][N:2]([C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13])[CH2:3][c:4]1[c:11]([Sn](C)(C)C)[c:8]([C:9]#[N:10])[n:6]([CH3:7])[n:5]1.[CH3:19][O:20][c:21]1[c:27]([NH2:28])[n:26][c:25](Br)[c:23]([Br:24])[cH:22]1>>[CH3:19][O:20][c:21]1[c:27]([NH2:28])[n:26][c:25]([c:11]2[c:8]([C:9]#[N:10])[n:6]([CH3:7])[n:5][c:4]2[CH2:3][N:2]([C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13])[CH3:1])[c:23]([Br:24])[cH:22]1

Participants

6

Reactant 2

HCID 178483110HCID 178483110, compoundHCID 178486943HCID 178486943, compound

Product 1

HCID 178486944HCID 178486944, compound

Reagents, catalysts & solvents 3

HCID 75537289[1,1-bis(diphenylphosphino)ferrocene]dichloropalladium(II) dichlormethaneCatalystHCID 8028TetrahydrofuranSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
50 °C

Sources & evidence

ORD record
ord-f635315d35a54568ba862fb607b3279e
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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