N-methyl-2-pyrrolidone → {3-[4-(2,2-Difluoroethyl)phenyl]-5-[3-(2-methoxyethyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}(thiomorpholin-4-yl)methanone
Reaction equation
[CH2:38]1[CH2:39][S:40][CH2:41][CH2:42][NH:43]1.[CH3:53][N:54]1[CH2:55][CH2:56][CH2:57][C:58]1=[O:59].[CH:44]([N:45]([CH2:46][CH3:47])[CH:48]([CH3:49])[CH3:50])([CH3:51])[CH3:52].[F:1][CH:2]([CH2:3][c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH2:11][N:12]([C:25](=[O:26])[O:27][c:28]3[cH:29][cH:30][c:31]([N+:32]([O-:33])=[O:34])[cH:35][cH:36]3)[CH2:13][CH:14]([c:16]3[n:17][c:18]([CH2:21][CH2:22][O:23][CH3:24])[n:19][o:20]3)[CH2:15]2)[cH:8][cH:9]1)[F:37]>>[F:1][CH:2]([CH2:3][c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH2:11][N:12]([C:25](=[O:26])[N:43]3[CH2:38][CH2:39][S:40][CH2:41][CH2:42]3)[CH2:13][CH:14]([c:16]3[n:17][c:18]([CH2:21][CH2:22][O:23][CH3:24])[n:19][o:20]3)[CH2:15]2)[cH:8][cH:9]1)[F:37]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-cc088505ed6549e3afe9ce2b664137f9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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