Tetrahydrofuran → 2-(2-fluoro-4-iodophenylamino)-1,5-dimethyl-6-oxo-N-(2-(vinyloxy)ethoxy)-1,6-dihydropyridine-3-carboxamide
Reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:30][Si:31]([N-:32][Si:33]([CH3:34])([CH3:35])[CH3:36])([CH3:37])[CH3:38].[CH:23](=[CH2:24])[O:25][CH2:26][CH2:27][O:28][NH2:29].[F:1][c:2]1[c:3]([NH:9][c:10]2[n:11]([CH3:22])[c:12](=[O:21])[c:13]([CH3:20])[cH:14][c:15]2[C:16]([O:18][CH3:17])=[O:19])[cH:4][cH:5][c:6]([I:8])[cH:7]1.[Li+:39]>>[F:1][c:2]1[c:3]([NH:9][c:10]2[n:11]([CH3:22])[c:12](=[O:21])[c:13]([CH3:20])[cH:14][c:15]2[C:16](=[O:18])[NH:29][O:28][CH2:27][CH2:26][O:25][CH:23]=[CH2:24])[cH:4][cH:5][c:6]([I:8])[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-dbcd9817216c43aea1fcbac0f6bfafda
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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