Tetrahydrofuran → (2-((2,6-Dimethyl-1-piperidinyl)methyl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methanol
Reaction equation
[Al+3:2].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:7][CH:8]1[N:9]([CH2:15][c:16]2[c:17](-[c:26]3[c:27]([F:34])[cH:28][cH:29][c:30]([O:32][CH3:33])[cH:31]3)[cH:18][cH:19][c:20]([C:22](=[O:23])[O:24][CH3:25])[cH:21]2)[CH:10]([CH3:14])[CH2:11][CH2:12][CH2:13]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3]>>[CH3:7][CH:8]1[N:9]([CH2:15][c:16]2[c:17](-[c:26]3[c:27]([F:34])[cH:28][cH:29][c:30]([O:32][CH3:33])[cH:31]3)[cH:18][cH:19][c:20]([CH2:22][OH:23])[cH:21]2)[CH:10]([CH3:14])[CH2:11][CH2:12][CH2:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a296966842e14174aee5d9d17864f881
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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