2,4,6-Trichloropyrimidine → HCID 65710860, compound

HRID 2018490Notes

Reaction equation

HRID 2018490 reaction equation
[CH3:1][c:2]1[c:7](B2OC(C)(C)C(C)(C)O2)[cH:6][n:4]([CH3:5])[n:3]1.Cl[c:8]1[n:15][c:13]([Cl:14])[n:12][c:10]([Cl:11])[cH:9]1>>[CH3:1][c:2]1[c:7]([c:8]2[n:15][c:13]([Cl:14])[n:12][c:10]([Cl:11])[cH:9]2)[cH:6][n:4]([CH3:5])[n:3]1

Participants

8

Reactant 2

HCID 773782,4,6-TrichloropyrimidineHCID 426473161,3-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Product 1

HCID 65710860HCID 65710860, compound

Reagents, catalysts & solvents 5

HCID 962WaterReagentHCID 516892Sodium BicarbonateReagentHCID 2734558Bis(tri-tert-butylphosphine)palladium(0)CatalystHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
60 °C

Sources & evidence

ORD record
ord-4077f743ca9c4b54b6fd9540260a200d
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

Loading…