Bis(pinacolato)diborane → HCID 89808005, compound

HRID 2018819Notes

Reaction equation

HRID 2018819 reaction equation
[CH3:1][CH:2]([c:11]1[c:16]([C:17]([N:19]([CH2:21][c:22]2[n:26]([CH3:27])[n:25][c:24]([C:28]([CH3:31])([CH3:30])[CH3:29])[c:23]2Br)[CH3:20])=[O:18])[n:15][cH:14][cH:13][cH:12]1)[O:3][c:4]3[c:9]([NH2:10])[n:8][cH:7][c:6](I)[cH:5]3.CC1(C(C)(C)OB(B2OC(C)(C)C(C)(C)O2)O1)C>>[CH3:1][CH:2]1[c:11]([c:16]2[C:17](=[O:18])[N:19]([CH3:20])[CH2:21][c:22]3[c:23]([c:24]([C:28]([CH3:31])([CH3:30])[CH3:29])[n:25][n:26]3[CH3:27])[c:6]4[cH:5][c:4]([c:9]([NH2:10])[n:8][cH:7]4)[O:3]1)[cH:12][cH:13][cH:14][n:15]2

Participants

8

Reactant 2

HCID 2733548Bis(pinacolato)diboraneHCID 178462229HCID 178462229, compound

Product 1

HCID 89808005HCID 89808005, compound

Reagents, catalysts & solvents 5

HCID 962WaterReagentHCID 25953Cesium fluorideReagentHCID 11979704Tetrakis(triphenylphosphine)palladiumCatalystHCID 887MethanolSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-b5c24668e5b5430391bb98766043d6ff
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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